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The reasons for the 20% failure rate include inaccurate diagnosis; misidentification of the pathogen; and the presence of a second disorder, such as psoriasis ().

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Minimum length of therapy for canine superficial pyoderma is 3 to 4 weeks.

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Griseofulvin is effective only against fungal organisms that affect the skin and hair.

Antifungal activity remains in the skin for 2 months after the plasma concentration has depleted, following cessation of medication.

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Thus, any proposed clinical uses are based for the most part on in vitro data and the results of in vivo studies in experimental animal infection models.

In case you notice any of these mentioned symptoms you should stop applying this remedy on your skin.

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In some infections, the fungus will not be in a circle and can spread across the face or nose and look like an autoimmune disease or other generalized skin disease.

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Pulse therapy with itraconazole is effective, because the drug persists in therapeutic concentrations in fingernails for up to 3 months and in toenails for up to 6 months after the completion of therapy ().

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The reaction may be related to an allergy, or it may be a direct toxic effect from the substance.

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J) Bioconversion of ligninWhite Rot fungi such as Coriolus versicolor, Polyporus ance and Brown Rotfungi like Poria monticola, Lenzitis trabea are used in depolymerization anddegradation of lignin to low molecular weight Petroleum products.

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This paper explores new concepts in the treatment of median nail dystrophy (MND), onychomycosis, and the nail pathology of hand, foot, and mouth disease (HFMD).

The enzyme inducer, griseofulvin, decreases the effect of the hormone agent, conjugated estrogens.

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Serum salicylate concentrations may be decreased when Griseofulvin is given concomitantly with salicylates.

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Suppression of spermatogenesis has been reported to occur in rats and sperm abnormalities have been observed in griseofulvin treated mice, but these were not detected in man.

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Smith J, Safdar N, Knasinski V, Simmons W, Bhavnani S, Ambrose P, Andes D (April 2006).

Itraconazole and fluconazole have been shown to be safe and effective, but are not FDA-approved for this indication.

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As a 1% cream or powder, it is used for superficial skin infections such as (tinea cruris), (tinea pedis), and other types of (tinea corporis).

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Inhibition of this enzyme causes squalene, a substance toxic to fungal cells, to accumulate intracellularly and leads to rapid cell death.

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The compound has limited affinity for tissues but is detectable in the skin within 3 h of initial therapy.

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When adverse reactions occur, they are most commonly of the hypersensitivity type such as skin rashes, urticaria, erythema, multiform-like drug reactions, and rarely, angioneurotic edema, and may necessitate withdrawal of therapy and appropriate countermeasures.

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The enzyme inducer, griseofulvin, decreases the effect of the hormone agent, medroxyprogesterone.

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